Informations for Students
Topics of the part on hematology and oncology in the main lecture internal medicine:
- Physiology and pathophysiology of the hematopoietic system; the hierarchy of stem cells;
- the role of cytokines in cell proliferation and differentiation;
- function of mature hematopoietic cells; differentiation pathways;
- morphology of normal and pathological hematopoietic cells;
- clonal evolution and the development of malignancy;
- aplastic anemia; clinics and therapy of aplastic anemia;
- iron-deficiency anemia;
- vitamin B12 deficiency;
- hemolytic anemias;
- paroxysmal nocturnal hemoglobinuria;
- hemoglobinopathies;
- antibody-mediated hemolysis;
- clinics and supportve therapy of bone marrow failure;
- clinical considerations in transfusion-therapy; therapy of neutropenic infections;
- classification, clinics and treatment of acute myeloid leukemia and myelodysplasia;
- chronic myeloid leukemia and other chronic myeloproliferative disorders;
- classification; biology; clinical picture and treatment of malignant non-Hodgkin's lymphomas;
- mantle cell lymphoma;
- follicular lymphoma;
- marginal zone lymphoma;
- immunocytoma;
- multiple myeloma;
- chronic lymphocytic leukemia;
- diffuse large cell lymphoma and other high-grade malignant lymphomas;
- acute lymphocytoic leukemia;
- Burkitt's-NHL;
- Hodgkin's disease;
- T cell neoplasia and mycosis fungoides;
- angioimmunoblastic lymphadenopathy;
- malignant melanoma;
- high-dose chemotherapy and blood stem cell transplantation;
- physiology and pathology of hemostasis;
- acquired and hereditary disorders of coagulation;
- hemophilia;
- disseminated intravascular coagulation;
- diagnostics and therapy of thrombosis;
- antithrombin III;
- protein S;
- protein C;
- APC resistance;
- colon and rectum cancer
- lung cancer
- testis cancer
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